Keep an eye on Carefully (1)pentobarbital will lessen the extent or result of hydrocodone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Closely. Caution when discontinuing CYP3A4 inducers which are coadministered with hydrocodone; plasma concentrations of hydrocodone could boost and may end up in probably fatal respiratory depressionSerious - Use Option (one)hydrocodone, pentobarbital.
Contraindicated (1)pentobarbital will lower the extent or effect of doravirine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the extent or result of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will decrease the extent or result of fostemsavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
Caution when discontinuing CYP3A4 inducers that happen to be coadministered with hydrocodone; plasma concentrations of hydrocodone might raise and can result in perhaps lethal respiratory depression
pentobarbital will reduce the level or impact of tofacitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Loss of, or reduced response to tofacitinib might happen when coadministered with potent CYP3A4 inducers
pentobarbital will minimize the level or result of triamcinolone acetonide injectable suspension by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
This drug may perhaps interfere Using the absorption of orally administered griseofulvin, reducing its blood stages; consequences of blood amount reduction unknown; preferable to prevent concomitant administration of those medications
Keep track of Closely (one)pentobarbital will reduce the level or result of gefitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lower the extent or outcome of parecoxib by affecting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Observe.
pentobarbital will lower the Nembutal level or effect of isavuconazonium sulfate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will decrease the level or effect of lopinavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
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Estradiol valerate/dienogest shouldn't be employed for at least 28 times right after discontinuation of the inducer as a consequence of probability of reduced contraceptive efficacy.